Measurements Of Response, Remission & Recovery In Schizophrenia & Examples For Their Clinical Application
Key Messages
The treatment outcomes of response, remission, and recovery have different meanings to schizophrenia researchers vs clinicians.
Linking rating scale results to Clinical Global Impression (CGI) scores helps them to be more easily understood and applied clinically, and reveals that the widely used response cutoff of 20% for other scales (e.g., Positive and Negative Syndrome Scale [PANSS] and Brief Psychiatric Rating Scale [BPRS]) does not reflect clinically meaningful improvement in patients with acute, non-refractory schizophrenia.
Standardization of outcome evaluation may allow for …