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How Should Residual Symptoms Be Defined in Depressed Patients Who Have Remitted?

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Recognition of remission in patients with depression who have responded to treatment has clinical implications, as the presence of residual symptoms in treatment responders predicts an increased likelihood of relapse and greater psychosocial morbidity.
This study compared the prevalence of residual symptoms estimated by different cutoff scores of 2 self-reported measures of depression and determined associations between residual symptoms and indices of psychosocial morbidity (eg, psychosocial functioning and quality of life [QoL]).
Patients with major depressive disorder (MDD) who achieved remission …

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