Inflammation In Neurological & Psychiatric Diseases
Key Messages
This review article examined findings on the relationship of inflammation with neurological and psychiatric disorders.
Several lines of evidence supported the role of inflammation in the pathophysiology of depression and schizophrenia, including altered levels of proinflammatory cytokines and inflammatory biomarkers in individuals with these conditions. The authors proposed that peripheral immune mediators infiltrating the central nervous system (CNS) may elicit the behavioral symptoms of depression through their adverse effects on relevant neurotransmitter systems and hypothalamic−pituitary−adrenal (HPA) axis balance.
Background
The following is …
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