Exploring Unresolved Symptoms In Major Depressive Disorder (MDD): Potential Role Of Norepinephrine

Join us for a PsychU on-demand webinar exploring unresolved symptoms in major depressive disorder (MDD) and the potential role of norepinephrine, as part of the monoaminergic theory of depression.

Despite the efficacy of first-line anti-depressant treatments in MDD, many individuals continue to experience unresolved symptoms that may impair their daily functioning and increase the healthcare burden. In fact, the STAR*D study demonstrated approximately one third of patients with MDD achieved remission following treatment with first-line antidepressants, highlighting the need to address unresolved and persistent symptoms of depression.¹ Recent studies have shown that norepinephrine, a neurotransmitter which regulates concentration, energy levels, and arousal, may play a crucial role in the persistence of depression symptoms.²

Watch Drs. Roger McIntyre and John Awad as they discuss the potential role of norepinephrine in depression and the challenges of identifying and treating unresolved depression symptoms. Our on-demand webinar aims to provide valuable insights into the complex nature of depression and the potential for treatments to address unresolved symptoms of depression.

References:

1. Rush AJ et al. Am J Psychiatry. 2006;163:1905-1917
2. Maletic V, et al. Front Psychiatry. 2017;8:42.

Roger S. McIntyre, MD, FRCPC

Professor of Psychiatry and Pharmacology, University of Toronto, Head of the Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, Canada

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Dr. Roger McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network, Toronto, Canada; Executive Director of the Brain and Cognition Discovery Foundation in Toronto, Canada, Director as well as Co-Chair of the Scientific Advisory Board of the Depression and Bipolar Support Alliance (DBSA) from Chicago, Illinois; Professor and Nanshan Scholar at Guangzhou Medical University; Adjunct Professor at College of Medicine in Korea University; and Clinical Professor at State University of New York (SUNY) Upstate Medical University, Syracuse, New York, USA, and at Department of Psychiatry and Neurosciences University of California School of Medicine, Riverside, California, USA. Dr. McIntyre completed his medical degree at Dalhousie University. He received his Psychiatry residency training and Fellowship in Psychiatric Pharmacology at the University of Toronto.

John Awad, MD (OPDC)

Senior Medical Science Liaison

Roger McIntyre is a paid consultant of Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC)
John Awad is an employee of Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC)