MedThink Archives - Page 2 of 2

Do Inflammation & Metabolic Disturbances Metastasize To The Brain? Implications For Disease Modeling & Novel Approaches In Psychiatry (Inflammation Series Part 1)

On-Demand Webinar February 14, 2017

During this webinar, Dr. Roger S. McIntyre, Professor of Psychiatry and Pharmacology (University of Toronto), Head of the Mood Disorders Psychopharmacology Unit (University Health Network), and Executive Director of the… Read More

Medication Adherence In Patients With Bipolar Disorder: A Comprehensive Review

Article January 31, 2017

Key Messages Medication nonadherence in patients with bipolar disorder (BD) is common and can be attributed to a number of patient-level and external barriers. Several strategies have been identified that… Read More

Is Age Of Onset Associated With Severity, Prognosis & Clinical Features In Bipolar Disorder? A Meta-Analytic Review

Article January 6, 2017

Key Messages The relationship between age at onset (AAO) of bipolar disorder (BD) and clinical presentation and specific outcomes is unclear, as individual studies have reported mixed results. In this… Read More

Cognitive Impairment In First-Episode Mania: A Systematic Review Of The Evidence In The Acute & Remission Phases Of The Illness

Article December 21, 2016

Key Messages First-episode mania (FEM) is a crucial time in the disease course of bipolar disorder (BD) because several cognitive changes are thought to occur during this time. There is… Read More

Inter-Relation Between Brain-Derived Neurotrophic Factor & Antioxidant Enzymes In Bipolar Disorder

Article December 21, 2016

Key Messages Abnormal regulation of brain-derived neurotrophic factor (BDNF) and reactive oxygen species, both of which play key roles in the pathophysiology of bipolar disorder (BD), may be interrelated and… Read More

Sleep, Residual Mood Symptoms & Time To Relapse In Recovered Patients With Bipolar Disorder

Article December 21, 2016

Key Messages Sleep disturbance is commonly observed in patients with bipolar disorder (BD), during mood episodes and when they experience residual symptoms between episodes. Compared with healthy individuals, recovered patients… Read More

Course & Outcome Following A First Episode Of Mania: Four-Year Prospective Data From The Systematic Treatment Optimization Program (STOP-EM)

Article December 21, 2016

Key Messages Understanding the course of bipolar I disorder (BD) following the first episode of mania may help identify opportunities for early intervention. Minimizing recurrence within the first year of… Read More

The Role Of Sleep In Bipolar Disorder

Article December 21, 2016

Key Messages Patients with bipolar disorder (BD) commonly experience sleep disturbances, which are negatively associated with treatment outcomes, throughout all stages of the illness. Sleep disturbances in patients with BD… Read More

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